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You'll usually take or use sumatriptan once a migraine or cluster headache has started. It is not a painkiller but you can use this medicine if painkillers or non-steroidal anti-inflammatory drugs (NSAIDs) have not worked.
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If you find tablets difficult to swallow, some sumatriptan tablets have a score line to help you break them in half. Check the information leaflet inside the medicine packet to see if you can do this with your medicine.
These common side effects of sumatriptan happen in more than 1 in 100 people. They're usually mild and do not last long. Some of the side effects are similar to the symptoms of migraine or cluster headaches. There are things you can do to help cope with them:
If you're taking antidepressants, check with your doctor whether it's safe to take sumatriptan with your other medicines. Using sumatriptan with some types of antidepressants can increase your risk of a severe side effect called serotonin syndrome.
There's not enough information to say that other complementary medicines, herbal remedies and supplements are safe to take with sumatriptan. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
We supply Imigran nasal sprays (10mg & 20mg) and sumatriptan tablets in 50mg and 100mg strengths for the relief of migraines. 'Sumatriptan' is the active ingredient in Imigran. Generic sumatriptan tablets cost less than branded Imigran tablets, but are medically the same (see generic medicines FAQs page).
Migraine occurs when blood vessels in the head widen temporarily. Sumatriptan tablets and nasal sprays reduce the widening of the blood vessels and this helps to relieve headache and other migraine symptoms.
Sumatriptan (Imigran) belongs to a group of medicines called triptans, and should not be taken at the same time as other triptans used to treat migraine, including naratriptan, rizatriptan, and zolmitriptan. Other migraine treatments may interact, namely ergotamine or similar medicines. Leave at least 24 hours between taking these medications and sumatriptan. See the 'other medicines' section of the manufacturers leaflet for further details.
There is no evidence of increased risk of birth defects with sumatriptan in pregnancy, but there is only limited information. The risks and benefits of treatment should be discussed with a doctor before taking sumatriptan in pregnancy.
Common side effects with sumatriptan tablets and Imigran spray (affecting up to 1 in 10 people) may include: aching muscles, shortness of breath, dizziness, tiredness, nausea (feeling sick), temporary increase in blood pressure.
It is best to start treatment as soon as you feel a migraine headache coming on, although treatment can be used any time during an attack. Imigran (sumatriptan) doesn't work if started during the aura phase.
Imigran nasal spray comes in a single dose bubble pack and should be stored in the pack until use. There is a 20mg and a 10mg strength. Adults 18 to 65 years usually use one 20mg spray into just one nostril. But one 10mg spray into one nostril is enough for some people. The dose can be repeated after 2 hours if required, but only if there was improvement with the first dose. If symptoms have resolved completely, there is no need to repeat the dose. Maximum of 2 sprays in 24 hours. Not to be used at the same time as sumatriptan tablets or other triptan tablets.
Sumatriptan tablets are not a preventative for use when there are no symptoms. They work best if taken as soon as a migraine headache is coming on, but can be taken any time after the headache has started. Do not take during the aura phase. The usual dose is one 50mg tablet, swallowed whole, but some people require the higher strength 100mg tablet. You can take a second tablet after 2 hours, but only if symptoms are continuing and have partially responded to the first tablet. The maximum dose in 24 hours is 300mg (6 x 50mg tablets or 3 x 100mg tablets). Not to be used at the same time as the Imigran spray or other triptan medications.
If vomiting is marked, an anti-sickness tablet or suppository can help. Some migraine tablets contain a combination of painkillers and antiemetics. Painkillers which contain codeine and other 'opiates' should usually be avoided as they can increase sickness and are potentially addictive.
People who get frequent migraines, sometimes defined as two or more attacks a month, or where acute treatment is not effective, may be suitable for long term preventative treatments, such as daily beta-blocker tablets or other medicines. Consult with your GP to discuss these treatment options.
Very effective for Cluster Headaches too. Works best on an empty stomach.I often break these in half as 50mg is good enough but the 100mg pills are the same price as the 50 mg pills, strangely enough.
This medication may also be used as a backup for sumatriptan injection. If your symptoms are only partly relieved or your headache comes back, you may take a dose of sumatriptan by mouth at least two hours after the injection, up to a maximum of 100 milligrams in a 24-hour period.
If you have a higher risk for heart problems (see Precautions), your doctor may perform a heart exam before you start taking sumatriptan. He/she may also direct you to take your first dose of this medication in the office/clinic to monitor for serious side effects (such as chest pain). Talk to your doctor for details.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions Before using sumatriptan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
If you also take any ergotamine medication (such as dihydroergotamine) or other "triptan" drugs (such as zolmitriptan, rizatriptan), you will need to separate your sumatriptan dose from your dose of these other medications to lessen the chance of serious side effects. Ask your doctor how long you should wait between your doses of these drugs. Does Sumatriptan Succinate interact with other drugs you are taking? Enter your medication into the WebMD interaction checker Check Interaction Overdose If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Notes Do not share this medication with others.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Images sumatriptan 100 mg tablet
Data from a prospective pregnancy exposure registry and epidemiological studies of pregnant women have not detected an increased frequency of birth defects or a consistent pattern of birth defects among women exposed to sumatriptan compared with the general population (see Data). In developmental toxicity studies in rats and rabbits, oral administration of sumatriptan to pregnant animals was associated with embryolethality, fetal abnormalities, and pup mortality. When administered by the intravenous route to pregnant rabbits, sumatriptan was embryolethal (see Data).
Human Data: The Sumatriptan/Naratriptan/Treximet (sumatriptan and naproxen sodium) Pregnancy Registry, a population-based international prospective study, collected data for sumatriptan from January 1996 to September 2012. The Registry documented outcomes of 626 infants and fetuses exposed to sumatriptan during pregnancy (528 with earliest exposure during the first trimester, 78 during the second trimester, 16 during the third trimester, and 4 unknown). The occurrence of major birth defects (excluding fetal deaths and induced abortions without reported defects and all spontaneous pregnancy losses) during first-trimester exposure to sumatriptan was 4.2% (20/478 [95% CI: 2.6% to 6.5%]) and during any trimester of exposure was 4.2% (24/576 [95% CI: 2.7% to 6.2%]). The sample size in this study had 80% power to detect at least a 1.73- to 1.91-fold increase in the rate of major malformations. The number of exposed pregnancy outcomes accumulated during the registry was insufficient to support definitive conclusions about overall malformation risk or for making comparisons of the frequencies of specific birth defects. Of the 20 infants with reported birth defects after exposure to sumatriptan in the first trimester, 4 infants had ventricular septal defects, including one infant who was exposed to both sumatriptan and naratriptan, and 3 infants had pyloric stenosis. No other birth defect was reported for more than 2 infants in this group.
In a study using data from the Swedish Medical Birth Register, live births to women who reported using triptans or ergots during pregnancy were compared with those of women who did not. Of the 2,257 births with first-trimester exposure to sumatriptan, 107 infants were born with malformations (relative risk 0.99 [95% CI: 0.91 to 1.21]). A study using linked data from the Medical Birth Registry of Norway to the Norwegian Prescription Database compared pregnancy outcomes in women who redeemed prescriptions for triptans during pregnancy, as well as a migraine disease comparison group who redeemed prescriptions for sumatriptan before pregnancy only, compared with a population control group. Of the 415 women who redeemed prescriptions for sumatriptan during the first trimester, 15 had infants with major congenital malformations (OR 1.16 [95% CI: 0.69 to 1.94]) while for the 364 women who redeemed prescriptions for sumatriptan before, but not during, pregnancy, 20 had infants with major congenital malformations (OR 1.83 [95% CI: 1.17 to 2.88]), each compared with the population comparison group. Additional smaller observational studies evaluating use of sumatriptan during pregnancy have not suggested an increased risk of teratogenicity. 041b061a72